[HTML][HTML] The effect of zoledronic acid on type and volume of Modic changes among patients with low back pain
K Koivisto, J Järvinen, J Karppinen, M Haapea… - BMC Musculoskeletal …, 2017 - Springer
… changes in size and type of MC, after a single intravenous infusion of 5 mg zoledronic acid
(ZA) or placebo, among chronic LBP patients with … the MRI changes correlate with symptoms. …
(ZA) or placebo, among chronic LBP patients with … the MRI changes correlate with symptoms. …
[HTML][HTML] The effect of zoledronic acid on serum biomarkers among patients with chronic low back pain and modic changes in lumbar magnetic resonance imaging
K Koivisto, J Karppinen, M Haapea, J Järvinen… - Diagnostics, 2019 - mdpi.com
… We analyzed the MRIs for type and volume of each MC from sagittal images at a clinical
workstation (Neaview Radiology, version 2.23, Neagen Corporation, Oulu, Finland) [23]. MC …
workstation (Neaview Radiology, version 2.23, Neagen Corporation, Oulu, Finland) [23]. MC …
Effect of zoledronic acid and denosumab in patients with low back pain and modic change: a proof‐of‐principle trial
… effect of zoledronic acid (ZA) and denosumab on low back pain (LBP) and Modic change (…
Adults aged ≥40 years with significant LBP for at least 6 months duration and MC (type 1, 2, …
Adults aged ≥40 years with significant LBP for at least 6 months duration and MC (type 1, 2, …
[HTML][HTML] Efficacy of zoledronic acid for chronic low back pain associated with Modic changes in magnetic resonance imaging
K Koivisto, E Kyllönen, M Haapea, J Niinimäki… - BMC Musculoskeletal …, 2014 - Springer
… The patients were well informed of possible adverse effects; this may have contributed to a
large amount of reports of acute phase reaction symptoms. Some of the main determinants of …
large amount of reports of acute phase reaction symptoms. Some of the main determinants of …
Oral Zoledronic acid bisphosphonate for the treatment of chronic low back pain with associated Modic changes: A pilot randomized controlled trial
GKH Shea, C Zhang, WS Suen… - Journal of …, 2022 - Wiley Online Library
… Zoledronic acid is a potent bisphosphonate that has … or less volume/extent of MC affecting
the vertebral body/subchondral bone region. In further support, a recent study among patients …
the vertebral body/subchondral bone region. In further support, a recent study among patients …
[PDF][PDF] Effect of zoledronic acid and denosumab in patients with low back pain and Modic change: a proof of principle trial 2
PO GDipSci, D Speden - figshare.utas.edu.au
… this study was to evaluate the effect of zoledronic acid (ZA) and denosumab on low 25 … effect
of zoledronic acid on type and volume of Modic changes among patients with low back pain. …
of zoledronic acid on type and volume of Modic changes among patients with low back pain. …
Clinical efficacy of calcitonin compared to diclofenac sodium in chronic nonspecific low back pain with type I Modic changes: a retrospective study
J Zhou, T Li, L Li, Y Xue - Journal of Pain Research, 2018 - Taylor & Francis
… zoledronic acid had a positive efficacy in the treatment of LBP with MC, with mild to moderate
side effects… , renal function must be monitored during zoledronic acid treatment. Hence, we …
side effects… , renal function must be monitored during zoledronic acid treatment. Hence, we …
[PDF][PDF] Non-surgical therapy for the treatment of chronic low back pain in patients with Modic changes: A systematic review of the literature
X Mu, W Peng, Y Ou, P Li, Z Li, J Wei - Heliyon, 2022 - cell.com
… The percentage of patients with grade 1 Modic changes (… volume was observed in the
antibiotic group, where changes … Should zoledronic acid be used as a conservative treatment …
antibiotic group, where changes … Should zoledronic acid be used as a conservative treatment …
Placebo-controlled Trial of Oral Vitamin D and Alendronate Efficacy for Pain and Modic Changes in Lumbar Fusion Surgery
K Haddadi, M Mehriyari, S Ehteshami, S Shafiee… - Iranian Journal of …, 2022 - irjns.org
… in patients with low back pain, and Modic changes undergoing … However, in terms of quantity
and quality data, it was less … The zoledronic acid effect was confirmed in decreasing the …
and quality data, it was less … The zoledronic acid effect was confirmed in decreasing the …
Serum biomarkers for Modic changes in patients with chronic low back pain
J Karppinen, K Koivisto, J Ketola, M Haapea… - European Spine …, 2021 - Springer
… Lumbar Modic change (MC) can serve as a diagnostic marker as well as an independent
source of chronic low back pain (… Type or volume of MC was not associated with biomarker …
source of chronic low back pain (… Type or volume of MC was not associated with biomarker …